Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pdia7Protein disulfide-isomerase. (488 aa)    
Predicted Functional Partners:
calr
Calreticulin.
   
 0.997
tap2a
Transporter-associated with antigen-processing, subunit type a.
   
 0.978
tap1
Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP).
   
  0.978
calr3b
Calreticulin.
   
 0.977
calr3a
Calreticulin.
   
 0.976
tap2t
Transporter-associated with antigen-processing, subunit type t, teleost-specific.
   
  0.959
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
   
0.950
tapbp.1
TAP-binding protein (tapasin), tandem duplicate 1.
    
 0.950
pdia8
Protein disulfide-isomerase.
     
  0.950
pdia3
Protein disulfide-isomerase.
     
  0.950
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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