Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdgfrlPlatelet-derived growth factor receptor-like. (371 aa)    
Predicted Functional Partners:
pdgfd
Platelet-derived growth factor d.
    
 0.760
ngfa
Neurotrophin-7; Recombinant ZNT-7 was able to bind to the human p75 neurotrophin receptor/NGFR and to induce tyrosine phosphorylation of the rat NTRK1/TRKA receptor tyrosine kinase, albeit less efficiently than rat NGF. ZNT-7 did not interact with rat NTRK2/TRKB or NTRK3/TRKC, indicating a similar receptor specificity as NGF; Belongs to the NGF-beta family.
  
 
 0.756
grin3a
Glutamate receptor, ionotropic, N-methyl-D-aspartate 3A.
      
 0.710
pdgfrb
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.701
pon2
Paraoxonase 2.
   
  
 0.688
pdgfc
Platelet-derived growth factor c; Belongs to the PDGF/VEGF growth factor family.
    
 0.682
shc1
SHC (Src homology 2 domain-containing)-transforming protein 1.
   
 0.682
SHC3
SHC adaptor protein 3.
   
 0.682
kitlga
Kit ligand a.
    
 0.653
vegfc
Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family.
    
  0.652
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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