Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
slc10a2Solute carrier family 10 (Sodium/bile acid cotransporter family), member 2. (361 aa)    
Predicted Functional Partners:
abcb11b
ATP-binding cassette, sub-family B (MDR/TAP), member 11b.
   
  
 0.785
fabp6
Fatty acid-binding protein 6, ileal (gastrotropin).
   
  
 0.766
slc10a7
Sodium/bile acid cotransporter 7; Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper functioning extracellular matrix (By similarity). Required for extracellular matrix mineralization. Also involved in the regulation of cellular calcium homeostasis (By similarity). Does not show transport activity towards bile acids or steroid sulfates.
      
 0.761
nepro
Nucleolus and neural progenitor protein; May play a role in the Notch signaling pathway. Belongs to the nepro family.
      
 0.747
tmigd1
Transmembrane and immunoglobulin domain-containing 1.
   
  
 0.716
abcb11a
ATP-binding cassette, sub-family B (MDR/TAP), member 11a.
   
  
 0.693
tlr20.1
Toll-like receptor 20, tandem duplicate 1.
 
    
 0.667
nr1h4
Nuclear receptor subfamily 1, group H, member 4.
   
  
 0.627
cyp8b1
Cytochrome P450, family 8, subfamily B, polypeptide 1.
   
  
 0.612
gpbar1
G protein-coupled bile acid receptor 1.
      
 0.583
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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