Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pdha1aPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (393 aa)    
Predicted Functional Partners:
pdhb
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.999
dlat
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.999
pdhx
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.999
dldh
Dihydrolipoyl dehydrogenase.
 
 
 0.998
bckdhb
Branched chain keto acid dehydrogenase E1 subunit beta.
 
 0.983
ldha
L-lactate dehydrogenase A chain; Belongs to the LDH/MDH superfamily. LDH family.
  
 0.961
g6pd
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.
   
 0.950
ldhba
L-lactate dehydrogenase B-A chain; Belongs to the LDH/MDH superfamily. LDH family.
  
 0.947
me2
Malic enzyme.
   
 0.947
h6pd
Hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase).
   
 0.941
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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