Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
adh8aAlcohol dehydrogenase 8a. (377 aa)    
Predicted Functional Partners:
esd
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
 0.989
aldh16a1
Aldehyde dehydrogenase 16 family, member A1.
  
 0.942
aldh3a1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.930
aldh9a1b
4-trimethylaminobutyraldehyde dehydrogenase B; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency.
  
 0.924
adh5
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
  
  
0.921
aldh7a1
Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family.
  
 0.921
aldh3a2b
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 0.905
aldh9a1a.2
Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family.
  
 0.899
akr1a1b
Aldo-keto reductase family 1 member A1-B; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids. Acts as an aldehyde-detoxification enzyme (By similarity). Displays no reductase activity towards retinoids (By similarity).
    
 0.896
aldh1a2
Aldehyde dehydrogenase 1 family, member A2; Belongs to the aldehyde dehydrogenase family.
  
 0.890
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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