STRINGSTRING
scn8aa protein (Danio rerio) - STRING interaction network
"scn8aa" - Sodium channel, voltage-gated, type VIII, alpha a in Danio rerio
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
scn8aaSodium channel, voltage-gated, type VIII, alpha a; Mediates the voltage-dependent sodium ion permeability of excitable membranes (1949 aa)    
Predicted Functional Partners:
ENSDARG00000031427
Calmodulin 2b, (phosphorylase kinase, delta) (149 aa)
       
 
  0.987
scn8ab
Sodium channel, voltage-gated, type VIII, alpha b; Mediates the voltage-dependent sodium ion permeability of excitable membranes (1958 aa)
     
 
0.983
scn4ab
Sodium channel, voltage-gated, type IV, alpha, b; This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle (1784 aa)
     
 
0.982
scn4aa
Sodium channel, voltage-gated, type IV, alpha, a; This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle (1829 aa)
     
 
0.982
scn12aa
Sodium channel, voltage gated, type XII, alpha a ; Mediates the voltage-dependent sodium ion permeability of excitable membranes (1027 aa)
     
 
0.982
scn1lab
Sodium channel, voltage-gated, type I like, alpha b; Mediates the voltage-dependent sodium ion permeability of excitable membranes (1996 aa)
     
 
0.927
ENSDARG00000078758
Uncharacterized protein (1841 aa)
     
 
0.923
calm1a
Calmodulin 1b; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (149 aa)
       
 
  0.920
ENSDARG00000034187
Calmodulin 3a (phosphorylase kinase, delta) (149 aa)
     
 
  0.919
ENSDARG00000074057
Calmodulin 3a (phosphorylase kinase, delta) (149 aa)
       
 
  0.915
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio, Brachydanio rerio, Brachydanio rerio frankei, Celestichthys, Cyprinidae, Cypriniformes, Cypriniphysi, Cyprinoidea, Cyprinoidei, Cyprinus rerio, D. rerio, Danio, Danio frankei, Danio rerio, Danio rerio frankei, Ostariophysi, Otocephala, Otophysi, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (14%) [HD]