STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ctnsCystinosin, lysosomal cystine transporter. (384 aa)    
Predicted Functional Partners:
slc66a1
Solute carrier family 66 member 1.
   
 
 0.935
shpk
Sedoheptulokinase.
   
  
 0.806
lrp2a
Low density lipoprotein receptor-related protein 2a.
      
 0.734
btg3
B-cell translocation gene 3.
      
 0.664
ybx1
Y-box-binding protein 1; DNA- and RNA-binding protein involved in various processes, such as translational repression, RNA stabilization, mRNA splicing and transcription regulation. Binds preferentially to the 5'-[CU]CUGCG-3' RNA motif and specifically recognizes mRNA transcripts modified by C5-methylcytosine (m5C). Promotes mRNA stabilization: acts by binding to m5C- containing mRNAs and recruiting pabpc1a, thereby preventing mRNA decay. Plays a role in the maternal-to-zygotic transition in early embryo by binding to m5C-containing maternal mRNAs and preventing their degradation. Also [...]
      
 0.626
hs1bp3
HCLS1-binding protein 3.
   
    0.609
mfsd12a
Major facilitator superfamily domain-containing 12a.
   
  
 0.604
cln3
Battenin.
   
  
 0.571
ocrl
OCRL inositol polyphosphate-5-phosphatase.
      
 0.567
F1QYP6_DANRE
Carboxypeptidase; Belongs to the peptidase S10 family.
   
  
 0.551
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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