Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
asap2aArfGAP with SH3 domain, ankyrin repeat and PH domain 2a. (991 aa)    
Predicted Functional Partners:
asap3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3.
    
  0.827
arf6b
ADP-ribosylation factor 6a; Belongs to the small GTPase superfamily. Arf family.
    
 0.722
arf6a
ADP-ribosylation factor 6a.
    
 0.722
appl2
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper-containing 2.
    
 0.655
appl1
HESX homeobox 1.
    
 0.655
grb2b
Growth factor receptor-bound protein 2b.
    
 
 0.592
grb2a
Growth factor receptor-bound protein 2a.
    
 
 0.592
exoc7
Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
      
 0.545
arfgap1
ADP-ribosylation factor GTPase-activating protein 1.
    
 0.545
sh3kbp1
SH3-domain kinase-binding protein 1.
   
 
 0.490
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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