Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lamc1Laminin subunit gamma-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. (1593 aa)    
Predicted Functional Partners:
dag1
Dystroglycan 1.
   
 0.933
lamb1a
Laminin, beta 1a.
   
0.929
itga4
Integrin alpha 4; Belongs to the integrin alpha chain family.
    
 0.924
Itga7
Uncharacterized protein.
    
 0.924
itgb4
Integrin beta.
   
 0.922
itga3b
Integrin, alpha 3b; Belongs to the integrin alpha chain family.
   
 0.914
lamb1b
Laminin, beta 1b.
   
0.913
itga6l
Integrin, alpha 6,-like; Belongs to the integrin alpha chain family.
    
 0.913
itgb5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.910
lamb2l
Laminin, beta 2-like.
   
0.909
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.