STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mark3aNon-specific serine/threonine protein kinase. (722 aa)    
Predicted Functional Partners:
LOC110440168
EWS RNA-binding protein 1b.
      
 0.805
cmtr1
Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1; S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG- capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.
   
  
 0.731
ewsr1b
Ewing sarcoma breakpoint region 1b.
   
  
 0.721
TOM1L2
Target of myb1 like 2 membrane trafficking protein; Belongs to the TOM1 family.
      
 0.719
tom1l2
Target of myb1-like 2 membrane-trafficking protein; Belongs to the TOM1 family.
      
 0.719
ppp1r12c
Protein phosphatase 1, regulatory subunit 12C.
   
 
 0.687
kif21a
Kinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.580
fubp1
Far upstream element (FUSE)-binding protein 1.
   
  
 0.573
vps39
VPS39 subunit of HOPS complex.
   
  
 0.542
pfkfb2b
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2b.
      
 0.541
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.