STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lgsnLengsin, lens protein with glutamine synthetase domain; Belongs to the glutamine synthetase family. (668 aa)    
Predicted Functional Partners:
tyw3
tRNA wybutosine-synthesizing protein 3 homolog; Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity).
      
 0.842
gmps
Guanine monophosphate synthase.
    
 0.810
crygn1
Gamma-crystallin N-A; Crystallins are the dominant structural components of the vertebrate eye lens.
   
  
 0.792
grifin
Grifin; Binds lactose.
   
  
 0.787
crygmx
Crystallin, gamma MX; Belongs to the beta/gamma-crystallin family.
   
  
 0.779
lim2.2
Lens intrinsic membrane protein 2.2.
   
  
 0.758
crygmxl2
Crystallin, gamma MX,-like 2; Belongs to the beta/gamma-crystallin family.
   
  
 0.741
aldh18a1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  
  
 0.732
iah1
Isoamyl acetate-hydrolyzing esterase 1 homolog; Probable lipase.
  
 
 0.721
cryzl1
Crystallin, zeta (Quinone reductase)-like 1.
      
 0.720
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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