Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ugt5a1UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (525 aa)    
Predicted Functional Partners:
gusb
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family.
     
 0.879
akr1a1b
Aldo-keto reductase family 1 member A1-B; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids. Acts as an aldehyde-detoxification enzyme (By similarity). Displays no reductase activity towards retinoids (By similarity).
   
 
 0.875
blvra
Biliverdin reductase A.
     
 0.874
cyp1b1
Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
   
  0.874
aox6
Aldehyde oxidase beta.
   
 
 0.874
ces2b
Si:ch211-93f2.1; Belongs to the type-B carboxylesterase/lipase family.
     
 0.873
hsd11b1la
Hydroxysteroid 11-beta-dehydrogenase 1-like protein.
    
  0.871
miox
Inositol oxygenase; Belongs to the myo-inositol oxygenase family.
     
  0.871
hsd17b2
Hydroxysteroid (17-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
  0.869
cyp3a65
Cytochrome P450, family 3, subfamily A, polypeptide 65; Belongs to the cytochrome P450 family.
    
 0.869
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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