node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ahctf1 | c19h1orf109 | ENSDARP00000128519 | ENSDARP00000025246 | AT hook-containing transcription factor 1. | Uncharacterized protein C1orf109 homolog; Plays an essential role in early embryonic development. | 0.745 |
ahctf1 | mtbp | ENSDARP00000128519 | ENSDARP00000137105 | AT hook-containing transcription factor 1. | MDM2-binding protein. | 0.555 |
ahctf1 | snrnp48 | ENSDARP00000128519 | ENSDARP00000136650 | AT hook-containing transcription factor 1. | Small nuclear ribonucleoprotein 48 (U11/U12). | 0.509 |
ahctf1 | spc24 | ENSDARP00000128519 | ENSDARP00000059307 | AT hook-containing transcription factor 1. | Kinetochore protein Spc24; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. | 0.664 |
c19h1orf109 | ahctf1 | ENSDARP00000025246 | ENSDARP00000128519 | Uncharacterized protein C1orf109 homolog; Plays an essential role in early embryonic development. | AT hook-containing transcription factor 1. | 0.745 |
c19h1orf109 | cwc25 | ENSDARP00000025246 | ENSDARP00000091697 | Uncharacterized protein C1orf109 homolog; Plays an essential role in early embryonic development. | CWC25 spliceosome-associated protein homolog. | 0.793 |
c19h1orf109 | ftsj1 | ENSDARP00000025246 | ENSDARP00000074130 | Uncharacterized protein C1orf109 homolog; Plays an essential role in early embryonic development. | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.718 |
c19h1orf109 | lix1 | ENSDARP00000025246 | ENSDARP00000114322 | Uncharacterized protein C1orf109 homolog; Plays an essential role in early embryonic development. | Limb and CNS-expressed 1. | 0.694 |
c19h1orf109 | lix1l | ENSDARP00000025246 | ENSDARP00000115243 | Uncharacterized protein C1orf109 homolog; Plays an essential role in early embryonic development. | Limb and CNS-expressed 1-like. | 0.694 |
c19h1orf109 | mocs3 | ENSDARP00000025246 | ENSDARP00000013020 | Uncharacterized protein C1orf109 homolog; Plays an essential role in early embryonic development. | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a. Its N-terminus first activates urm1 and mocs2a as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.711 |
c19h1orf109 | mtbp | ENSDARP00000025246 | ENSDARP00000137105 | Uncharacterized protein C1orf109 homolog; Plays an essential role in early embryonic development. | MDM2-binding protein. | 0.860 |
c19h1orf109 | rubcnl | ENSDARP00000025246 | ENSDARP00000113588 | Uncharacterized protein C1orf109 homolog; Plays an essential role in early embryonic development. | Rubicon-like autophagy enhancer. | 0.793 |
c19h1orf109 | snrnp48 | ENSDARP00000025246 | ENSDARP00000136650 | Uncharacterized protein C1orf109 homolog; Plays an essential role in early embryonic development. | Small nuclear ribonucleoprotein 48 (U11/U12). | 0.811 |
c19h1orf109 | spc24 | ENSDARP00000025246 | ENSDARP00000059307 | Uncharacterized protein C1orf109 homolog; Plays an essential role in early embryonic development. | Kinetochore protein Spc24; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. | 0.866 |
cwc25 | c19h1orf109 | ENSDARP00000091697 | ENSDARP00000025246 | CWC25 spliceosome-associated protein homolog. | Uncharacterized protein C1orf109 homolog; Plays an essential role in early embryonic development. | 0.793 |
cwc25 | ftsj1 | ENSDARP00000091697 | ENSDARP00000074130 | CWC25 spliceosome-associated protein homolog. | Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. | 0.719 |
cwc25 | lix1 | ENSDARP00000091697 | ENSDARP00000114322 | CWC25 spliceosome-associated protein homolog. | Limb and CNS-expressed 1. | 0.694 |
cwc25 | lix1l | ENSDARP00000091697 | ENSDARP00000115243 | CWC25 spliceosome-associated protein homolog. | Limb and CNS-expressed 1-like. | 0.694 |
cwc25 | mocs3 | ENSDARP00000091697 | ENSDARP00000013020 | CWC25 spliceosome-associated protein homolog. | Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a. Its N-terminus first activates urm1 and mocs2a as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.719 |
cwc25 | rubcnl | ENSDARP00000091697 | ENSDARP00000113588 | CWC25 spliceosome-associated protein homolog. | Rubicon-like autophagy enhancer. | 0.793 |