Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pon2Paraoxonase 2. (355 aa)    
Predicted Functional Partners:
lamb2l
Laminin, beta 2-like.
   
  
 0.800
pdgfrl
Platelet-derived growth factor receptor-like.
   
  
 0.688
ucmab
Unique cartilage matrix-associated protein C-terminal fragment; May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface. Belongs to the UCMA family.
      
 0.681
si:dkey-32e6.6
Si:dkey-32e6.6.
      
 0.669
nfyc
Nuclear transcription factor Y, gamma.
    
   0.652
ecm2
Extracellular matrix protein 2, female organ and adipocyte-specific.
   
  
 0.609
si:dkey-6n6.1
Si:dkey-6n6.1.
      
 0.597
col4a6
Collagen, type IV, alpha 6.
      
 0.596
cnmd
Leukocyte cell-derived chemotaxin 1; Bifunctional growth regulator. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization (By similarity); Belongs to the chondromodulin-1 family.
      
 0.578
Q1MT21_DANRE
Si:ch211-284e20.8.
   
  
 0.496
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.