Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nuak1aNUAK family, SNF1-like kinase, 1a. (617 aa)    
Predicted Functional Partners:
ecrg4b
Augurin-B; Probable hormone (By similarity). Required for the proper formation of the central nervous system by attenuating cell proliferation during development (By similarity). Belongs to the augurin family.
      
 0.684
arhgap12a
Rho GTPase-activating protein 12a.
      
 0.666
usp9
Ubiquitin-specific peptidase 9; Belongs to the peptidase C19 family.
    
 
 0.604
sh2d3a
SH2 domain containing 3A.
      
 0.594
arhgap12b
Rho GTPase-activating protein 12b.
      
 0.565
arhgap17a
Rho GTPase-activating protein 17a.
      
 0.560
LOC101882092
Wu:fc23c09.
      
 0.552
wwtr1
WW domain-containing transcription regulator 1.
      
 0.546
arhgap28
Rho GTPase-activating protein 28.
   
  
 0.514
arhgap27
Rho GTPase-activating protein 27.
      
 0.501
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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