Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kcnk6Potassium channel, subfamily K, member 6; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (324 aa)    
Predicted Functional Partners:
kcnc4
Potassium voltage-gated channel, Shaw-related subfamily, member 4; Belongs to the potassium channel family.
   
 
 0.788
crebl2
cAMP-responsive element-binding protein-like 2; Probable regulator of creb1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle (By similarity).
      
 0.784
lrrc8da
Leucine-rich repeat-containing 8 VRAC subunit Da.
      
 0.780
kcnj13
Potassium inwardly rectifying channel subfamily J member 13.
     
 0.727
slc24a2
Solute carrier family 24 member 2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.718
slc41a2b
Solute carrier family 41 member 2b.
      
 0.697
magt1
Magnesium transporter protein 1; Cell surface magnesium transporter.
      
 0.662
zgc:66426
Zgc:66426.
      
 0.652
kcng4a
Potassium voltage-gated channel, subfamily G, member 4a; Belongs to the potassium channel family.
   
 
 0.630
ano10a
Anoctamin-10; Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1 (By similarity).
      
 0.619
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.