Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
apoa1aProapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). (262 aa)    
Predicted Functional Partners:
apoba
Apolipoprotein Ba.
   
 0.989
apoc2
Apolipoprotein C-II.
   
 
 0.969
apoc1
Apolipoprotein C-I.
   
 
 0.969
apobb.2
Apolipoprotein Bb, tandem duplicate 2.
   
 0.968
apoeb
Apolipoprotein Eb; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. Belongs to the apolipoprotein A1/A4/E family.
   
 
0.962
apoea
Apolipoprotein Ea.
  
 
0.957
apoa4b.1
Apolipoprotein A-IV b, tandem duplicate 1.
  
 
0.951
apoa1b
Apolipoprotein A-Ib.
  
 
0.918
zgc:162608
Zgc:162608.
   
 
  0.908
abca1a
ATP-binding cassette, sub-family A (ABC1), member 1A.
     
 0.901
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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