Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
isl1lIslet1,-like. (323 aa)    
Predicted Functional Partners:
gcat
Glycine C-acetyltransferase.
      
 0.594
dnaja2a
DnaJ heat shock protein family (Hsp40) member A2a.
    
 
 0.577
LOC101882228
FH2 domain-containing protein.
      
 0.565
mcm5
DNA helicase; Belongs to the MCM family.
      
 0.560
kirrel3a
Kirre-like nephrin family adhesion molecule 3a.
    
 
 0.521
trmo
tRNA methyltransferase O.
   
  
 0.498
wdr90
WD repeat domain 90.
    
   0.442
tbx2a
T-box transcription factor 2a.
    
 
 0.411
bmp7b
Bone morphogenetic protein 7b.
    
 
 0.406
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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