Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
syap1Synapse-associated protein 1. (334 aa)    
Predicted Functional Partners:
pin1
Peptidyl-prolyl cis-trans isomerase.
    
   0.967
reps2
RALBP1-associated Eps domain-containing 2.
      
 0.840
ap1s2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
      
 0.813
AP1S2
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
      
 0.813
nt5c1aa
5'-nucleotidase, cytosolic IAa.
   
  
 0.785
pgm2l1
Phosphoglucomutase 2-like 1.
      
 0.760
eml2
EMAP-like 2.
      
 0.736
heca
Hdc homolog, cell cycle regulator.
      
 0.700
noc4l
Nucleolar complex protein 4 homolog.
      
 0.697
vipas39
Spermatogenesis-defective protein 39 homolog; Proposed to be involved in endosomal maturation implicating in part vps33b. In epithelial cells, the vps33b:vipas39 complex may play a role in the apical rab11a-dependent recycling pathway and in the maintenance of the apical-basolateral polarity. May play a role in lysosomal trafficking, probably via association with the core HOPS complex in a discrete population of endosomes; the functions seems to be indepenedent of vps33b. May play a role in vesicular trafficking during spermatogenesis (By similarity). May be involved in direct or indir [...]
   
  
 0.661
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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