STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kctd5aPotassium channel tetramerization domain-containing 5a. (224 aa)    
Predicted Functional Partners:
cul3a
Cullin 3a; Belongs to the cullin family.
   
 0.969
cul3b
Cullin 3b; Belongs to the cullin family.
    
 0.969
kctd1
Potassium channel tetramerization domain-containing 1.
      
 0.821
kctd20
BTB domain-containing protein.
      
 0.735
kctd2
Potassium channel tetramerization domain-containing 2.
  
 
0.724
kctd10
Potassium channel tetramerisation domain containing 10.
     
0.696
KCTD15
Potassium channel tetramerization domain containing 15.
      
 0.681
klhl3
Kelch-like protein 3; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron.
    
 0.677
tnfaip1
Tumor necrosis factor, alpha-induced protein 1 (endothelial).
     
0.667
spop
Speckle-type POZ protein; Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. Belongs to the Tdpoz family.
     
 0.653
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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