Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
dcnDecorin; May affect the rate of fibrils formation. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (373 aa)    
Predicted Functional Partners:
tgfb1a
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.991
tgfb1b
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.983
tgfb3
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.980
tgfb5
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.979
tgfb2
Transforming growth factor, beta 2.
    
 0.972
ccdc80
Coiled-coil domain-containing protein 80; Promotes cell adhesion and matrix assembly; Belongs to the CCDC80 family.
   
 0.960
lum
Lumican.
  
  
0.956
sparc
Secreted protein, acidic, cysteine-rich (osteonectin).
   
  
 0.917
col6a1
Collagen, type VI, alpha 1.
   
 
 0.871
igf1
Insulin-like growth factor 1b.
     
 0.847
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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