Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
irx7Iroquois homeodomain transcription factor Ziro7. (314 aa)    
Predicted Functional Partners:
barhl2
BarH-class homeodomain transcription factor.
   
 
 0.700
hsf4
Heat shock transcription factor 4.
      
 0.602
trps1
Trichorhinophalangeal syndrome I.
    
 
 0.597
nme2a
Nucleoside diphosphate kinase.
      
 0.596
pbx1a
Pre-B-cell leukemia transcription factor 1a.
    
 
 0.591
lmo4b
LIM domain only 4, like.
    
 
 0.582
crygn2
Gamma-crystallin N-B; Crystallins are the dominant structural components of the vertebrate eye lens.
    
 
 0.580
pkdcca
Protein kinase domain-containing, cytoplasmic a.
      
 0.561
ccnjl
Cyclin J-like; Belongs to the cyclin family.
      
 0.551
opn4b
Mammalian-like melanopsin-3.
      
 0.529
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.