Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
znrf1E3 ubiquitin-protein ligase znrf1; E3 ubiquitin-protein ligase that plays a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity. (215 aa)    
Predicted Functional Partners:
ube2na
Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.889
ube2nb
Ubiquitin-conjugating enzyme E2N-like; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.889
CLEC3A
C-type lectin domain family 3 member A.
      
 0.745
allc
Allantoicase; Utilization of purines as secondary nitrogen sources, when primary sources are limiting; Belongs to the allantoicase family.
      
 0.718
cish
Cytokine inducible SH2-containing protein A.
      
 0.716
aqr
Aquarius intron-binding spliceosomal factor.
      
 0.703
bcl3
BCL3 transcription coactivator.
    
 
 0.697
ncf4
Neutrophil cytosolic factor 4.
      
 0.692
cxcr1
Chemokine (C-X-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.663
R4GF04_DANRE
Si:dkey-187i8.2.
      
 0.662
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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