Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hspb11Heat shock protein beta-11; Belongs to the small heat shock protein (HSP20) family. (205 aa)    
Predicted Functional Partners:
lmod2a
Leiomodin 2 (cardiac) a.
   
  
 0.782
arhgef12a
Rho guanine nucleotide exchange factor (GEF) 12a.
      
 0.681
znrf2a
Zinc and ring finger 2a.
      
 0.662
ldb3b
LIM domain-binding 3b.
   
 
 0.606
rcan1a
Regulator of calcineurin 1a.
      
 0.594
ankrd1b
Ankyrin repeat domain 1b (cardiac muscle).
    
 
 0.580
apcdd1l
Adenomatosis polyposis coli down-regulated 1-like.
    
 
 0.572
capn3b
Calpain 3b; Belongs to the peptidase C2 family.
      
 0.558
bag3
BCL2-associated athanogene 3.
   
 
 0.504
atp1a2a
Sodium/potassium-transporting ATPase subunit alpha.
   
  
 0.479
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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