| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C5H11orf54 | ccdc82 | ENSDARP00000148836 | ENSDARP00000026367 | Ester hydrolase C11orf54 homolog; Exhibits ester hydrolase activity on the substrate p- nitrophenyl acetate. | Coiled-coil domain-containing 82. | 0.605 |
| ccdc82 | C5H11orf54 | ENSDARP00000026367 | ENSDARP00000148836 | Coiled-coil domain-containing 82. | Ester hydrolase C11orf54 homolog; Exhibits ester hydrolase activity on the substrate p- nitrophenyl acetate. | 0.605 |
| ccdc82 | fan1 | ENSDARP00000026367 | ENSDARP00000084286 | Coiled-coil domain-containing 82. | Fanconi-associated nuclease 1; Nuclease required for the repair of DNA interstrand cross- links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination, probably in the resolution of homologous recombination intermediates. Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Probably keeps excising with 3'- flap annealing until i [...] | 0.607 |
| ccdc82 | gpalpp1 | ENSDARP00000026367 | ENSDARP00000030566 | Coiled-coil domain-containing 82. | GPALPP motifs-containing 1. | 0.714 |
| ccdc82 | lig1 | ENSDARP00000026367 | ENSDARP00000078609 | Coiled-coil domain-containing 82. | DNA ligase. | 0.469 |
| ccdc82 | lrrc39 | ENSDARP00000026367 | ENSDARP00000096455 | Coiled-coil domain-containing 82. | Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress (By similarity). May regulate expression of other M-band proteins via an SRF-dependent pathway (By similarity). Important for normal contractile function in heart. | 0.542 |
| ccdc82 | mlh3 | ENSDARP00000026367 | ENSDARP00000120332 | Coiled-coil domain-containing 82. | MutL homolog 3 (E. coli). | 0.603 |
| ccdc82 | ndufaf6 | ENSDARP00000026367 | ENSDARP00000070200 | Coiled-coil domain-containing 82. | NADH:ubiquinone oxidoreductase complex assembly factor 6. | 0.473 |
| ccdc82 | pms1 | ENSDARP00000026367 | ENSDARP00000001250 | Coiled-coil domain-containing 82. | PMS1 homolog 1, mismatch repair system component. | 0.603 |
| ccdc82 | tmem231 | ENSDARP00000026367 | ENSDARP00000061995 | Coiled-coil domain-containing 82. | Transmembrane protein 231; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity). | 0.473 |
| ccdc82 | wrnip1 | ENSDARP00000026367 | ENSDARP00000010591 | Coiled-coil domain-containing 82. | WRN helicase-interacting protein 1. | 0.494 |
| fan1 | ccdc82 | ENSDARP00000084286 | ENSDARP00000026367 | Fanconi-associated nuclease 1; Nuclease required for the repair of DNA interstrand cross- links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination, probably in the resolution of homologous recombination intermediates. Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Probably keeps excising with 3'- flap annealing until i [...] | Coiled-coil domain-containing 82. | 0.607 |
| fan1 | lig1 | ENSDARP00000084286 | ENSDARP00000078609 | Fanconi-associated nuclease 1; Nuclease required for the repair of DNA interstrand cross- links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination, probably in the resolution of homologous recombination intermediates. Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Probably keeps excising with 3'- flap annealing until i [...] | DNA ligase. | 0.542 |
| fan1 | mlh3 | ENSDARP00000084286 | ENSDARP00000120332 | Fanconi-associated nuclease 1; Nuclease required for the repair of DNA interstrand cross- links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination, probably in the resolution of homologous recombination intermediates. Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Probably keeps excising with 3'- flap annealing until i [...] | MutL homolog 3 (E. coli). | 0.807 |
| fan1 | pms1 | ENSDARP00000084286 | ENSDARP00000001250 | Fanconi-associated nuclease 1; Nuclease required for the repair of DNA interstrand cross- links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination, probably in the resolution of homologous recombination intermediates. Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Probably keeps excising with 3'- flap annealing until i [...] | PMS1 homolog 1, mismatch repair system component. | 0.989 |
| gpalpp1 | ccdc82 | ENSDARP00000030566 | ENSDARP00000026367 | GPALPP motifs-containing 1. | Coiled-coil domain-containing 82. | 0.714 |
| gpalpp1 | lrrc39 | ENSDARP00000030566 | ENSDARP00000096455 | GPALPP motifs-containing 1. | Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress (By similarity). May regulate expression of other M-band proteins via an SRF-dependent pathway (By similarity). Important for normal contractile function in heart. | 0.542 |
| lig1 | ccdc82 | ENSDARP00000078609 | ENSDARP00000026367 | DNA ligase. | Coiled-coil domain-containing 82. | 0.469 |
| lig1 | fan1 | ENSDARP00000078609 | ENSDARP00000084286 | DNA ligase. | Fanconi-associated nuclease 1; Nuclease required for the repair of DNA interstrand cross- links (ICL) recruited at sites of DNA damage by monoubiquitinated FANCD2. Specifically involved in repair of ICL-induced DNA breaks by being required for efficient homologous recombination, probably in the resolution of homologous recombination intermediates. Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Probably keeps excising with 3'- flap annealing until i [...] | 0.542 |
| lig1 | mlh3 | ENSDARP00000078609 | ENSDARP00000120332 | DNA ligase. | MutL homolog 3 (E. coli). | 0.425 |