Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rnlsRenalase, FAD-dependent amine oxidase. (344 aa)    
Predicted Functional Partners:
nit1
Nitrilase 1.
      
 0.760
mfsd6l
Major facilitator superfamily domain-containing protein 6-like.
      
 0.727
arhgef39
Rho guanine nucleotide exchange factor (GEF) 39.
      
 0.719
fech
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
    
 0.690
ppox
Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
     
 0.612
ENSDARP00000150024
Uncharacterized protein.
     
 0.612
mrps18a
Mitochondrial ribosomal protein S18A.
      
 0.601
tapt1b
Transmembrane anterior posterior transformation protein 1 homolog; Plays a role in primary cilia formation. Involved in cartilage and bone development. May play a role in the differentiation of cranial neural crest cells. May act as a downstream effector of hoxc8 during development (By similarity).
      
 0.561
iars2
Isoleucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
  
 0.558
pank4
Pantothenate kinase 4 (inactive).
      
 0.558
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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