Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dnajc11aDnaJ (Hsp40) homolog, subfamily C, member 11a. (563 aa)    
Predicted Functional Partners:
armc1
Armadillo repeat-containing protein 1.
    
 
 0.925
chchd3a
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
    
 
 0.896
thap3
THAP domain-containing, apoptosis-associated protein 3.
   
  
 0.895
mtx2
Mtx2 protein.
   
 
 0.892
immt
MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
   
 
 0.859
rnf152
E3 ubiquitin-protein ligase rnf152; E3 ubiquitin-protein ligase mediating 'Lys-63'-linked polyubiquitination of RRAGA in response to amino acid starvation. Thereby, regulates mTORC1 signaling and plays a role in the cellular response to amino acid availability. Also mediates 'Lys-48'-linked polyubiquitination of target proteins and their subsequent targeting to the proteasome for degradation; Belongs to the RNF152 family.
      
 0.845
znf507
Zinc finger protein 507.
    
 
 0.819
get4
Guided entry of tail-anchored proteins factor 4.
    
 
 0.807
ints5
Integrator complex subunit 5.
    
 
 0.789
coa5
Cytochrome c oxidase assembly factor 5; Involved in an early step of the mitochondrial complex IV assembly process.
   
  
 0.786
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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