Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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Score
mettl21aProtein N-lysine methyltransferase METTL21A; Protein-lysine methyltransferase; Belongs to the methyltransferase superfamily. METTL21 family. (218 aa)    
Predicted Functional Partners:
METTL18
Si:dkey-15f17.8.
   
  
 0.964
hspbp1
HSPA (heat shock 70kDa)-binding protein, cytoplasmic cochaperone 1.
    
 
 0.935
kin
Kin17 DNA and RNA-binding protein.
   
  
 0.878
etfbkmt
Electron transfer flavoprotein beta subunit lysine methyltransferase; Protein-lysine methyltransferase that selectively trimethylates the flavoprotein ETFB in mitochondria. Thereby, may negatively regulate the function of ETFB in electron transfer from Acyl-CoA dehydrogenases to the main respiratory chain. Belongs to the methyltransferase superfamily. ETFBKMT family.
      
 0.872
eef1akmt1
EEF1A lysine methyltransferase 1; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'. Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
   
  
 0.869
hspa4b
Heat shock protein 4b.
   
 
 0.863
hspa4a
Heat shock protein 4, like.
   
 
 0.863
eef2kmt
Eukaryotic elongation factor 2 lysine methyltransferase.
   
 
 0.849
hspa8
Heat shock cognate 71 kDa protein; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis a [...]
    
 0.847
eef1akmt2
EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
   
  
 0.832
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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