Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pxmp2Peroxisomal membrane protein 2; Belongs to the peroxisomal membrane protein PXMP2/4 family. (194 aa)    
Predicted Functional Partners:
pex19
Peroxisomal biogenesis factor 19.
   
 0.984
pex3
Peroxisomal biogenesis factor 3.
   
 
 0.893
pex11b
Peroxisomal biogenesis factor 11 beta.
   
 
 0.873
pex16
Peroxisomal membrane protein PEX16; Involved in peroxisome biogenesis. Belongs to the peroxin-16 family.
   
 
 0.865
wu:fe02h09
Peroxisomal membrane protein 4; Belongs to the peroxisomal membrane protein PXMP2/4 family.
     
 0.865
mpv17
Protein Mpv17; Involved in mitochondrial homeostasis, and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance. Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress (By similarity). Belongs to the peroxisomal membrane protein PXMP2/4 family.
   
 
 0.801
pex26
Peroxisomal biogenesis factor 26.
   
 
 0.783
abcd1
ATP-binding cassette sub-family D member 1; Plays a role in the transport of free very-long-chain fatty acids (VLCFAs) as well as their CoA-esters across the peroxisomal membrane by acting as an ATP-specific binding subunit releasing ADP after ATP hydrolysis (By similarity). Involved in oligodendrocyte patterning and myelination.
     
 0.776
atad1b
ATPase family AAA domain-containing protein 1-B; ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR). Required for NMDA-stimulated AMPAR internalization in an ATPase-dependent manner (By similarity).
   
 
 0.775
pex13
Peroxisomal biogenesis factor 13.
   
 
 0.762
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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