STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
edf1Endothelial differentiation-related factor 1 homolog; Probable transcriptional coactivator. (146 aa)    
Predicted Functional Partners:
faua
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
   0.994
faub
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
   0.993
rps3
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
  
 
 0.965
rps10
Ribosomal protein S10.
   
 
 0.934
mrps10
Probable 28S ribosomal protein S10, mitochondrial; Belongs to the universal ribosomal protein uS10 family.
   
 
 0.932
rpl35
60S ribosomal protein L35; Plays an essential role in early embryonic development. May act as a haploinsufficient tumor suppressor. Belongs to the universal ribosomal protein uL29 family.
  
 
 0.930
rack1
Guanine nucleotide-binding protein subunit beta-2-like 1; Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes (By similarity). Required for VANGL2 membrane localization, inhibits Wnt signaling and regulates cellular polarization and oriented cell division during gastrulation; Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
   
 
 0.921
rps21
40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family.
   
 
 0.911
rps3a
40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family.
   
 
 0.910
rps5
Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family.
   
   0.910
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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