Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gsnaGelsolin a. (729 aa)    
Predicted Functional Partners:
pip4k2aa
Similar to type II phosphatidylinositolphosphate kinase-alpha.
     
  0.871
pip5k1bb
Phosphatidylinositol-4-phosphate 5-kinase, type I, beta b.
     
  0.871
pip5k1ca
Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a.
     
  0.871
pikfyve
Phosphatidylinositol phosphate 5-kinase type III isoform d.
     
  0.871
acta1b
Actin alpha 1, skeletal muscle b.
    
 
 0.870
cfl1
Muscle cofilin 2; Belongs to the actin-binding proteins ADF family.
   
  
 0.825
cfl1l
Cofilin 1 (non-muscle),-like; Belongs to the actin-binding proteins ADF family.
      
 0.805
cfl2
Cofilin 2 (Muscle); Belongs to the actin-binding proteins ADF family.
   
  
 0.792
pip5k1ab
Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b.
     
  0.723
pip4k2ca
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma; May play an important role in the production of Phosphatidylinositol bisphosphate (PIP2).
     
  0.723
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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