STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lmo7aLIM domain 7a. (1826 aa)    
Predicted Functional Partners:
afdna
Afadin, adherens junction formation factor a.
    
0.967
actn1
Actinin, alpha 1.
   
  0.901
actn4
Actinin, alpha 4.
    
  0.901
emd
Emerin (Emery-Dreifuss muscular dystrophy).
    
 
 0.842
pdlim3b
PDZ and LIM domain 3b.
   
 
 0.763
commd6
COMM domain-containing 6.
     
 0.686
actn3b
Actinin alpha 3b.
   
 
 0.683
pdlim7
PDZ and LIM domain protein 7; May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues (By similarity).
   
 
 0.678
pdlim5a
PDZ and LIM domain 5a.
   
 
 0.676
FBXO48
Si:dkey-202b17.4.
      
 0.627
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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