Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tbx15T-box transcription factor 15. (620 aa)    
Predicted Functional Partners:
cntnap3
Contactin-associated protein family member 3.
      
 0.768
actr10
Actin-related protein 10; Belongs to the actin family.
      
 0.726
Wars1
Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.621
wars2
Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.607
gdap2
Ganglioside-induced differentiation-associated protein 2; Belongs to the GDAP2 family.
      
 0.597
dchs2
Si:dkey-30k22.7.
      
 0.594
wars
Tryptophanyl-tRNA synthetase.
      
 0.576
tle3a
Transducin-like enhancer protein 3-A; Transcriptional corepressor that binds to a number of transcription factors. Enhances the transcriptional repression activity of pnx; Belongs to the WD repeat Groucho/TLE family.
    
 
 0.572
uncx4.1
Homeobox protein unc-4 homolog; Transcription factor involved in somitogenesis and neurogenesis; Belongs to the paired homeobox family. Unc-4 subfamily.
    
 
 0.534
spry2
Sprouty RTK-signaling antagonist 2.
      
 0.509
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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