STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmem178Transmembrane protein 178A; May act as a negative regulator of osteoclast differentiation; Belongs to the TMEM178 family. (301 aa)    
Predicted Functional Partners:
dhx57
DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57.
      
 0.866
kidins220b
Kinase D-interacting substrate of 220 kDa B; Downstream target for both neurotrophin and ephrin receptors. May play a role in nerve growth factor (NGF)-induced recruitment of rapgef2 to late endosomes and neurite outgrowth.
   
  
 0.744
csgalnact2
Hexosyltransferase.
      
 0.743
map4k3b
Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
   
  
 0.669
tmem94
Transmembrane protein 94.
      
 0.662
h3f3d
H3 histone, family 3D.
      
 0.645
h3f3a
H3 histone, family 3B.1.
      
 0.645
h3f3b.1
H3 histone, family 3B.1.
      
 0.645
h3f3c
H3 histone, family 3C.
      
 0.629
faf1
Fas (TNFRSF6)-associated factor 1.
      
 0.622
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.