STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmem178Transmembrane protein 178A; May act as a negative regulator of osteoclast differentiation; Belongs to the TMEM178 family. (301 aa)    
Predicted Functional Partners:
dhx57
DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57.
      
 0.836
csgalnact2
Hexosyltransferase.
      
 0.736
kidins220b
Kinase D-interacting substrate of 220 kDa B; Downstream target for both neurotrophin and ephrin receptors. May play a role in nerve growth factor (NGF)-induced recruitment of rapgef2 to late endosomes and neurite outgrowth.
      
 0.719
map4k3b
Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
      
 0.662
tmem94
Transmembrane protein 94.
      
 0.629
lancl2
LanC lantibiotic synthetase component C-like 2 (bacterial).
      
 0.595
faf1
Fas (TNFRSF6)-associated factor 1.
      
 0.589
h3f3d
H3 histone, family 3D.
      
 0.579
h3f3a
H3 histone, family 3B.1.
      
 0.579
h3f3b.1
H3 histone, family 3B.1.
      
 0.579
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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