Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
scxbScleraxis bHLH transcription factor b. (200 aa)    
Predicted Functional Partners:
bop1
Ribosome biogenesis protein bop1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
      
 0.683
xirp2a
Xin actin-binding repeat-containing 2a.
      
 0.683
actc1b
Actin, alpha 1, skeletal muscle.
    
 
 0.663
tnmd
Tenomodulin.
      
 0.595
thbs4b
Thrombospondin-4-B; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions and may be involved in various processes including cellular proliferation, migration, adhesion and attachment. May play a role in ER stress response (By similarity); Belongs to the thrombospondin family.
    
 
 0.595
tnnc2
Fast skeletal muscle troponin C.
      
 0.577
sox9a
HMG box transcription factor Sox9a.
    
 
 0.460
cyp26b1
Cytochrome P450 26B1; Involved in the metabolism of retinoic acid (RA), rendering this classical morphogen inactive through oxidation. Appears to be involved in the inactivation of all-trans-retinoic acid (RA). Plays a role in skeletal development; Belongs to the cytochrome P450 family.
    
 
 0.451
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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