Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rnpepArginyl aminopeptidase (Aminopeptidase B). (626 aa)    
Predicted Functional Partners:
zgc:162964
Zgc:162964.
   
  
 0.883
lta4h
Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family.
   
 
  0.670
pfdn1
Prefoldin subunit 1; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins (By similarity); Belongs to the prefoldin subunit beta family.
    
 
 0.663
mcrip1
Mapk-regulated corepressor-interacting protein 1; May play a role in the regulation of the epithelial- mesenchymal transition; Belongs to the MCRIP family.
      
 0.662
hpcal4
Hippocalcin-like 4.
      
 0.660
rasl12
Ras-like protein family member 12; Belongs to the small GTPase superfamily. Ras family.
      
 0.609
dpp3
Dipeptidyl peptidase 3; Belongs to the peptidase M49 family.
   
  
 0.598
itih3b
Inter-alpha-trypsin inhibitor heavy chain 3b.
    
 
 0.597
acbd3
Acyl-Coenzyme A-binding domain-containing 3.
   
  
 0.570
aacs
Acetoacetyl-CoA synthetase; Activates acetoacetate to acetoacetyl-CoA; Belongs to the ATP-dependent AMP-binding enzyme family.
      
 0.558
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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