Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
spicSpi-C transcription factor (Spi-1/PU.1-related). (263 aa)    
Predicted Functional Partners:
fhad1
Forkhead-associated (FHA) phosphopeptide-binding domain 1.
   
  
 0.744
ttr
Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.
      
 0.734
hoxd13a
Homeobox protein Hox-D13a; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
   
 
 0.722
ATP6
ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...]
      
 0.715
slc35f4
Solute carrier family 35 member F4.
      
 0.681
mcph1
Microcephalin 1.
      
 0.642
ano3
Anoctamin.
      
 0.628
cyp4v7
Cytochrome P450, family 4, subfamily V, polypeptide 7; Belongs to the cytochrome P450 family.
   
 0.617
scn1ba
Voltage-gated sodium channel beta 1 subunit splice variant D.
      
 0.603
scn1bb
Sodium channel, voltage-gated, type I, beta b.
      
 0.603
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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