Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dennd2dbDENN/MADD domain-containing 2Db. (488 aa)    
Predicted Functional Partners:
rab9b
RAB9B, member RAS oncogene family.
      
 0.788
dennd1b
DENN/MADD domain-containing 1B.
   
 
 0.761
rab15
RAB15, member RAS oncogene family.
   
  
 0.740
rab9a
RAB9A, member RAS oncogene family.
      
 0.682
dram2b
DNA-damage-regulated autophagy modulator 2b.
      
 0.661
rab35b
RAB35, member RAS oncogene family b.
   
 
 0.627
avl9
AVL9 homolog (S. cerevisiase).
      
 0.579
rab8b
RAB8B, member RAS oncogene family.
      
 0.573
ppfibp1a
PPFIA-binding protein 1a.
      
 0.573
tspan2a
Tetraspanin.
      
 0.571
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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