STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brwd3Bromodomain and WD repeat domain-containing 3. (1624 aa)    
Predicted Functional Partners:
sh3bgrl3
SH3 domain binding glutamic acid-rich protein like 3.
      
 0.810
sh3bgrl
SH3 domain-binding glutamic acid-rich-like protein; Belongs to the SH3BGR family.
      
 0.807
tmtc1
Transmembrane O-mannosyltransferase targeting cadherins 1.
   
 
 0.783
apool
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
   
  
 0.742
znf711
Zinc finger protein 711; Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes, leading to activate their expression (By similarity). Belongs to the krueppel C2H2-type zinc-finger protein family.
   
 
 0.686
arglu1a
Arginine and glutamate-rich protein 1-A; Belongs to the UPF0430 family.
   
 
 0.661
tbck
TBC1 domain-containing kinase.
      
 0.651
atrx
ATRX chromatin remodeler.
  
 
 0.633
kdm5c
Lysine (K)-specific demethylase 5C.
   
 
 0.607
ddb1
Damage-specific DNA-binding protein 1.
    
 
 0.590
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.