Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pank1bPantothenate kinase 1b. (451 aa)    
Predicted Functional Partners:
ppcs
Phosphopantothenoylcysteine synthetase.
     
 0.943
ppcdc
Phosphopantothenoylcysteine decarboxylase.
     
 0.941
coasy
CoA synthase.
     
 0.938
pank2
Pantothenate kinase 2.
     
  0.912
enpp2
Ectonucleotide pyrophosphatase/phosphodiesterase 2.
     
  0.818
enpp1
Ectonucleotide pyrophosphatase/phosphodiesterase 1.
     
  0.818
atp6v0cb
V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
      
 0.780
atp6v0a1b
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
   
  
 0.761
btd
Biotinidase.
     
 0.759
irak4
Interleukin-1 receptor-associated kinase 4.
    
  0.753
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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