Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMDHD1Probable imidazolonepropionase. (433 aa)    
Predicted Functional Partners:
ftcd
Formimidoyltransferase cyclodeaminase.
  
 
 0.990
uroc1
Urocanate hydratase 1.
  
 
 0.988
hal
Histidine ammonia-lyase; Belongs to the PAL/histidase family.
 
 
 0.942
I3IT94_DANRE
Si:dkey-156n14.3.
   
 
 0.927
abhd3
Abhydrolase domain-containing 3.
      
 0.772
enpp7.1
Ectonucleotide pyrophosphatase/phosphodiesterase 7, tandem duplicate 1.
      
 0.772
uprt
Uracil phosphoribosyltransferase homolog.
  
 
 0.767
hacd2
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...]
   
  
 0.740
cyp2ae1
Cytochrome P450, family 2, subfamily AE, polypeptide 1; Belongs to the cytochrome P450 family.
      
 0.737
uraha
5-hydroxyisourate hydrolase; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
  
  
 0.734
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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