Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dcaf13DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity). (445 aa)    
Predicted Functional Partners:
UTP14C
Si:dkey-251i10.3.
   
 
 0.988
wdr46
WD repeat domain 46.
   
 
 0.986
bysl
Bystin-like.
   
 
 0.984
bms1
BMS1 ribosome biogenesis factor.
   
 
 0.984
utp4
Cirrhosis, autosomal recessive 1A (Cirhin).
   
 
 0.983
wdr75
WD repeat-containing protein 75; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I.
   
 
 0.983
wdr43
WD repeat domain 43.
   
 
 0.983
wdr3
WD repeat domain 3.
   
 
 0.982
imp4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (Yeast).
   
 
 0.981
dcaf8
DDB1 and CUL4-associated factor 8.
     
 0.978
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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