Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cyt1Type I cytokeratin, enveloping layer; Belongs to the intermediate filament family. (429 aa)    
Predicted Functional Partners:
krt5
Keratin 5; Belongs to the intermediate filament family.
  
0.836
krt4
Keratin 4; Belongs to the intermediate filament family.
  
0.784
LOC100333286
Immunity-related GTPase family, e1.
    
 0.759
znf1156
Zinc finger protein 1156.
   
 0.752
zgc:158846
Zgc:158846; Belongs to the intermediate filament family.
  
0.731
krt8
Keratin, type II cytoskeletal 8; Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
  
0.713
cavin2b
Caveolae-associated protein 2b.
   
  
 0.694
ENSDARP00000131020
Si:ch211-195b11.3.
      
 0.662
F1RDG4_DANRE
Si:dkey-222f2.1; Belongs to the intermediate filament family.
  
 
0.618
acot21
Acyl-CoA thioesterase 21.
     
 0.591
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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