Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ube2bUbiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)    
Predicted Functional Partners:
rnf20
E3 ubiquitin protein ligase.
    
 0.990
ube2a
Ubiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.
  
  
0.901
ube2al
Ubiquitin-conjugating enzyme E2 A,-like; Belongs to the ubiquitin-conjugating enzyme family.
  
  
 
0.900
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.885
UBA6
Si:dkey-82j4.2.
   
 0.875
rad18
RAD18 E3 ubiquitin protein ligase.
    
 
 0.870
ube2v1
Ubiquitin-conjugating enzyme E2 variant 1.
    
 0.868
uba1
Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
  
 0.842
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
   
 0.829
rps27a
Ribosomal protein S27a.
    
 0.822
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.