STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dmtf1Cyclin-D-binding Myb-like transcription factor 1; Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53- dependent growth arrest. Binds to the consensus sequence 5'- CCCG[GT]ATGT-3'. (645 aa)    
Predicted Functional Partners:
armc1
Armadillo repeat-containing protein 1.
      
 0.958
rundc3b
RUN domain-containing protein 3B; Belongs to the RUNDC3 family.
      
 0.898
slc25a40
Solute carrier family 25 member 40.
      
 0.839
aip
Peptidylprolyl isomerase.
   
  
 0.744
dbf4
DBF4 zinc finger.
      
 0.583
crot
Carnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family.
   
  
 0.567
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated.
   
 
 0.562
abcb4
ATP-binding cassette, sub-family B (MDR/TAP), member 4.
      
 0.562
tdrd3
Tudor domain-containing protein 3; Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins (By simil [...]
   
  
 0.472
ccdc115
Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. May be involved in Golgi homeostasis.
      
 0.416
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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