Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
styxSerine/threonine/tyrosine-interacting protein. (224 aa)    
Predicted Functional Partners:
txndc16
Thioredoxin domain-containing 16.
      
 0.839
gpr137c
G protein-coupled receptor 137ba.
      
 0.751
faxdc2
Fatty acid hydroxylase domain-containing 2; Belongs to the sterol desaturase family.
      
 0.744
shoc2
Leucine-rich repeat protein SHOC-2; Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of raf1 kinase and stimulate raf1 activity at specialized signaling complexes (By similarity).
    
 
 0.739
fbxo38
F-box protein 38.
    
   0.720
gnpnat1
Glucosamine 6-phosphate N-acetyltransferase.
    
 
 0.706
fbxw7
F-box and WD repeat domain-containing 7.
    
 
 0.662
ddhd1b
DDHD domain-containing 1b.
      
 0.630
rtraf
RNA transcription, translation and transport factor protein; RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. Component of the tRNA-splicing ligase complex.
      
 0.611
psmc6
Proteasome (Prosome, macropain) 26S subunit, ATPase, 6; Belongs to the AAA ATPase family.
      
 0.584
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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