Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fth1bFerritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. (177 aa)    
Predicted Functional Partners:
fth1a
Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
  
  
 
0.964
fxn
Frataxin.
    
 0.893
cp
Ceruloplasmin; Belongs to the multicopper oxidase family.
     
 0.843
hephl1b
Hephaestin-like 1b; Belongs to the multicopper oxidase family.
     
 0.843
zgc:56095
Ferritin; Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
     
  0.830
ncoa4
Nuclear receptor coactivator 4.
     
  0.830
fech
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX.
     
 0.800
hephl1a
Hephaestin-like 1a; Belongs to the multicopper oxidase family.
     
 0.693
hmox1a
Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase.
  
 
 0.678
slc40a1
Solute carrier family 40 member 1; May be involved in iron export and also in transfer of iron between maternal and fetal circulation.
      
 0.606
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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