Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
klhl6Kelch-like family member 6. (614 aa)    
Predicted Functional Partners:
rc3h2
Ring finger and CCCH-type domains 2.
   
 
 0.946
SLA
Src like adaptor.
    
 
 0.892
cul3a
Cullin 3a; Belongs to the cullin family.
    
 0.886
cul3b
Cullin 3b; Belongs to the cullin family.
    
 0.886
klhdc2
Kelch domain-containing 2.
      
 0.756
ptpn21
Protein tyrosine phosphatase non-receptor type 21.
      
 0.729
dapp1
Dual adaptor of phosphotyrosine and 3-phosphoinositides.
   
 
 0.719
skap2
Src kinase-associated phosphoprotein 2; May be involved in B-cell and macrophage adhesion processes. May play a role in src signaling pathway (By similarity).
   
  
 0.718
pdgfc
Platelet-derived growth factor c; Belongs to the PDGF/VEGF growth factor family.
      
 0.692
nudcd3
NudC domain-containing 3.
    
 
 0.656
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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