Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
anxa1aAnnexin. (340 aa)    
Predicted Functional Partners:
s100a10a
Protein S100; Belongs to the S-100 family.
   
 0.984
s100a10b
Protein S100; Belongs to the S-100 family.
   
 0.915
ahnak
AHNAK nucleoprotein.
   
 0.772
icn
Protein S100; Belongs to the S-100 family.
   
 0.766
F1QQL4_DANRE
Si:ch211-125o16.4.
    
  0.750
fpr1
Formyl peptide receptor 1; Belongs to the G-protein coupled receptor 1 family.
     
 0.733
LOC795051
PDZ domain-containing protein.
   
 0.706
prx
Periaxin.
   
 0.706
dysf
Dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive).
   
 
 0.703
icn2
Protein S100; Belongs to the S-100 family.
   
 0.699
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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