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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dpp6bDipeptidyl-peptidase 6b; Belongs to the peptidase S9B family. (857 aa)    
Predicted Functional Partners:
zgc:136971
Zgc:136971.
      
 0.833
dpydb
Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine (By similarity); Belongs to the dihydropyrimidine dehydrogenase family.
      
 0.744
ptchd1
Patched domain-containing protein 1.
   
  
 0.683
ptchd4
Patched domain-containing protein 1.
   
  
 0.679
cbln4
Cerebellin 4 precursor.
   
  
 0.658
shank2b
SH3 and multiple ankyrin repeat domains 2b.
   
  
 0.629
syngap1b
Synaptic Ras GTPase-activating protein 1b.
   
  
 0.589
cbln2a
Cerebellin 2a precursor.
      
 0.570
kcnd3
Potassium voltage-gated channel, Shal-related subfamily, member 3; Belongs to the potassium channel family.
    
 
 0.566
kcnd1
Potassium voltage-gated channel, Shal-related subfamily, member 1; Belongs to the potassium channel family.
    
 
 0.566
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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